IGF-1受体,IGF-1 receptor
1)IGF-1 receptorIGF-1受体
1.Objective To observe the changes ofIGF-1 receptors in uterine leiomyoma and its correlation with estrogen receptor,progesterone receptor,PCNA and Bcl-2.目的观察人子宫肌瘤及周围正常子宫平滑肌组织中IGF-1受体、雌、孕激素受体、PCNA及Bcl-2含量的区别,并分析其相互关系。
2.In 3T3-L1 cells,IGF-1 receptor is located in lipid rafts and caveolae of the plasma membrane and can directly interact with caveolin-1, the major protein component in caveolae.我们的研究发现在3T3-L1前脂肪细胞分化诱导过程中，细胞膜上的脂质筏和质膜微囊结构对IGF-1受体的跨膜信号转导具有重要的作用，IGF-1受体的信号转导需要细胞膜上完整的脂质筏和质膜微囊结构。
3.Results Stimulation of D_1-like receptor inhibited theIGF-1 receptor expression,which was blocked by D_1-like receptor antagonist.方法本试验以A10细胞为研究对象,免疫印迹观察刺激D_1类受体对IGF-1受体表达的影响,并初步探讨D_1类受体对IGF-1受体影响的机制。
英文短句/例句
1.The Effect of D_1 Dopamine Receptor on IGF-1 Receptor Expression in Vascular Smooth Muscle Cells多巴胺D_1类受体对血管平滑肌细胞IGF-1受体表达的影响
2.Expression and Clinical Significance of EGF Receptor and IGF-1 Receptor in Nasopharyngeal CarcinomaEGF受体和IGF-1受体在人鼻咽癌组织中的表达及临床意义
3.Expression of IGF-1 and IGF-1R in prostate cancer and benign prostatic hyperplasiaIGF-1和其受体IGF-1R在前列腺癌和良性前列腺增生组织中的表达
4.Study on the Correlation between Expression Level of IGF-1 and It s Receptor in Goat Mammary Gland;羊乳腺中IGF-1与其受体基因表达量的相关性研究
5.The Growth Hormone Receptor (GHR) Exon 3 Polymorphism and Its Relationship with Metabolic Profile in Chinese Obesity ChildrenGHR、IGF-1、雌激素受体基因多态性与生长代谢的相关性研究
6.Expression of IGF-1 and IGF-1R in Uterine Leiomyoma and their Relation with Estrogen and ProgestogenIGF-1及其受体在子宫平滑肌瘤中的表达以及与雌、孕激素关系
7.Relationship between Fetal Growth Restriction and Maternal Serum IGF-1、IGFBP-1 and Leptin in the Third Trimerter;胎儿生长受限与IGF-1，IGFBP-1及Leptin的相关性研究
8.Expression of Receptors for GH/IGF-I and Estrogen in Shell Gland of Laying Hens;GH/IGF-I受体与雌激素受体在蛋鸡子宫中的表达
9.Anti-apoptotic effect of insulin-like growth factor 1 on blastocysts cells in vitroIGF-1对体外培养囊胚细胞抗凋亡的作用
10.Refolding and Purification of the Inclusion Body in rhIGF-1 & Manufacturing Process Study of LR~3-IGF-1rhIGF-1包涵体复性纯化及LR~3-IGF-1中试生产工艺研究
11.The Expression and Significance of IGF-1 and IGF-1R in Squamous Cell Carcinoma of Larynx;IGF-1和IGF-1R在喉鳞癌中的表达及意义
12.Construction of Antheraea Pernyi Nuclear Polyhedrosis Virus Double Promoter Transfer Vector Contains Genes of IGF-1 and GFP;构建携带IGF-1和GFP基因的柞蚕核型多角体病毒双启动子转移载体
13.Experimental Study on Bone Differentiation of Rabbit Bone Mesenchymal Stem Cells by Gene Transfection of Insulin Like Growth Factor-1IGF-1表达载体转染兔骨髓间充质干细胞体外成骨的实验研究
14.The in Vitro Anti-cancer Effects of Curcumin and Its Influence on the IGF-1 System in Human Cancer Cell Lines;姜黄素体外抗癌作用与IGF-1通路的关系及其机制研究
15.Chondrogenic Differentiation of Mesenchymal Stem Cells by Insulinlike Growth Factor-1 Gene Transfection with Liprofectamine;脂质体介导IGF-1基因修饰骨髓间充质干细胞成软骨分化
16.Human Degenerative Nucleus Pulposus Cell Culture in Vitro: Investigation of the Responsibility to Tissue Growth Factor-β1 and Insulin-like Growth Factor-1;退变人髓核细胞体外培养及对TGF-β1和IGF-1干预的反应性研究
17.Effects of Insulin-Like Growth Factor on the Proliferation and Differentiation of Cultured Neural Stem Cells of Embryonic Mice in Vitro;IGF-1对胚胎小鼠神经干细胞体外增殖和分化的影响
18.The Changes of Serum IGF-1, IGFBP-3 and the Pituitary Magnetic Resonance Imaging Study in Children with Short Stature;矮身材儿童血清IGF-1、IGFBP-3的改变和垂体MRI检查及其临床意义
相关短句/例句
IGF IRIGF-I受体
3)IGF RIGF受体
4)IGF type ⅠreceptorIGF Ⅰ型受体
5)insulin like growth factor I receptor(IGF-IR)胰岛素样生长因子1受体(IGF-1R)
6)Insulin-like Growth Factor receptor 1胰岛素样生长因子受体1(IGF-1R)
延伸阅读
IGF分子式：CAS号：性质：分子量7000的生长因子，IGF-I来源于成年的肝和其他部位平滑肌细胞，IGF-Ⅱ来源于胚胎肝、胎盘。靶细胞都是上皮细胞之间质细胞，刺激分化细胞的生长与修复，结构上约有50％的氨基酸序列与胰岛素同源，同时还与葡萄糖转运及代谢有关。也可用于Ⅱ型糖尿病的治疗。
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