血管内皮细胞生长因子-C,Vascular endothelial growth factor-C
1)Vascular endothelial growth factor-C血管内皮细胞生长因子-C
1.BACKGROUND & OBJECTIVE:Vascular endothelial growth factor-C (VEGF-C) could induce lymphangiogenesis in or around solid tumor, and is closely related with lymphatic metastasis.背景与目的:近年来研究发现,血管内皮细胞生长因子-C(vascularendothelialgrowthfactor-C,VEGF-C)可诱导实体瘤内或瘤周的淋巴管生成,与肿瘤的淋巴道转移密切相关。
英文短句/例句
1.Expression of vascular endothelial growth factor -C in tumor -associated macrophages and the clinico pathological significance in breast carcinoma血管内皮细胞生长因子-C在乳腺癌肿瘤相关巨噬细胞内的表达及临床意义
2.Effect of ionizing radiation on the expression of vascular endothelial growth factor-C gene in A549 cells of lung adenocarcinoma电离辐射对肺腺癌A549细胞血管内皮生长因子C基因表达的影响
3.Contradiction and Consideration of Vascular Endothelial Growth Factor Gene Therapy;关于血管内皮细胞生长因子基因治疗
4.Expression of Vascular Endothelial Growth Factor -A and -C, R-3mRNA in Laryngeal Squamous Cell Carcinoma;血管内皮生长因子A、C、受体3mRNA在喉鳞状细胞癌中的表达
5.Expression of Vascular Endothelial Growth Factor C(VEGF-C) and Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) in Transitional Cell Carcinoma (TCC) of Bladder;血管内皮生长因子C及其受体在膀胱移行细胞癌中的表达
6.Vascular Endothelial Growth Factor Enhances Focal Adhesion Kinase Expression and Activity in Hela Cervical Cancer Cells血管内皮生长因子C促进HeLa宫颈癌细胞粘着斑激酶活性的研究
7.The Research and application of vascular endothelial factor;血管内皮细胞生长因子的研究及应用
8.Effects of vascular endothelial growth factor on biological functions of bone marrow-derived endothelial progenitor cells血管内皮生长因子调节内皮祖细胞生物学功能
9.The Clinical Study of Cytokines and Growth of Vascular Endothelial Cells in Hepatocarcinoma;细胞因子与肝癌血管内皮细胞生长的临床研究
10.Variational trend of vascular endothelial growth factor in rat models of lower limb ischemia下肢缺血大鼠模型血管内皮细胞生长因子变化
11.Effects of endostatin on the expression of vascular endothelial growth factor in the retina of oxygen-induced retinal neovascularization内皮抑素对视网膜新生血管中血管内皮细胞生长因子表达的影响
12.The Expression of Extracellular Matrix Metalloproteinase Inducer and Vascular Endothelial Growth Factor C in Nasopharyngeal Carcinoma and Their Significance;细胞外基质金属蛋白酶诱导因子和血管内皮生长因子-C在鼻咽癌中的表达及其意义
13.Expressions and correlation of HIF-1α and VEGF-C in non-small cell lung cancer缺氧诱导因子-1α与血管内皮生长因子-C在非小细胞肺癌中的表达及相关性
14.The Effect and Mechanical Study of Vascular Endothelial Growth Factor on the Apoptosis of Vascular Endothelial Cell;血管内皮生长因子对血管内皮细胞凋亡的影响及其机理研究
15.The Influence of Vascular Endothelial Growth Factor on αv Integrin Expression of Vascular Endothelial Cells;血管内皮生长因子对血管内皮细胞αv整合素表达的影响
16.Role of Gravin on the Tubule-like Structure of Human Umbilical Vein Endothelial Cells Induced by Vascular Endothelial Growth FactorGravin参与血管内皮生长因子诱导的人脐静脉内皮细胞体外血管形成
17.The correlation between the lymph node involvement signs on computed tomography and VEGF-C as well as the lymphatic vessel density in non-small cell lung carcinoma非小细胞肺癌淋巴结转移CT表现与血管内皮生长因子-C及淋巴管生成的相关性研究
18.Effect of endostatin on growth and VEGF expression of HepG-2 Cells内皮抑素对肝癌HepG-2细胞生长和血管内皮生长因子表达的影响
相关短句/例句
Vascular endothelial growth factor C血管内皮细胞生长因子-C
3)Vascular endothelial growth factor C血管内皮细胞生长因子C
1.Objective:To investigate the roles of vascular endothelial growth factor C(VEGF-C) and tumor infiltrating dendritic cells(TIDC) in invasion and metastasis of gastric cancer cells and to investigate the relationship between VEGF-C expression and TIDC infiltration in gastric cancer.目的:探讨胃癌组织中血管内皮细胞生长因子C(vascular endothelial growth factor-c,VEGF-C)与肿瘤浸润性树突状细胞(tumor infiltrating dendritic cells,TIDC)在胃癌浸润转移中的作用及两者的关系。
4)VEGF-C·Stomach neoplasms·Tumor cells血管内皮生长因子C·胃肿瘤·肿瘤细胞
5)VEGF血管内皮细胞生长因子
1.HumanVEGF165 gene transfection into rat endothelial progenitor cells;人血管内皮细胞生长因子165基因转染大鼠内皮祖细胞的实验研究
2.Significance of expression MVD by means ofVEGF;血管内皮细胞生长因子表达肿瘤微血管密度的意义
3.Research on the Relationship Between SerumVEGF and Diabetic Vascular Complications;血清中血管内皮细胞生长因子含量与糖尿病血管合并症关系的研究
6)Vascular endothelial growth factor血管内皮细胞生长因子
1.Effects of Huoxue Bushen Mixture on skin blood vessel neogenesis and vascular endothelial growth factor expression in hair follicle of C57BL/6 mice;活血补肾合剂对C57BL/6小鼠皮肤血管新生及毛囊中血管内皮细胞生长因子表达的影响
2.Effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1α and vascular endothelial growth factor in granulation tissue of skin ulcers in rats with diabetes;益气化瘀中药对糖尿病皮肤溃疡大鼠缺氧诱导因子-1α和血管内皮细胞生长因子的影响
3.Down-regulation of vascular endothelial growth factor by Rosiglitazone in human lung adenocarcinoma cells;罗格列酮下调肺腺癌细胞血管内皮细胞生长因子的表达
延伸阅读
血管内皮生长因子分子式:CAS号:性质:又称血管通透因子(vascular permeability factor)。1989首先从牛垂体滤泡状细胞培养液中分离纯化。有四种不同形式,成熟单体,分别为121,165,189和206个氨基酸,目前分离得到的VEGF,均由两个相同多肽链通过二硫键构成的同源二聚体,亚基分子量18 000~24 000,总蛋白分子量34 000~46 000。蛋白质表面有许多阳离子,呈强碱性,等电点高,对酸碱热稳定。VEGF是一类糖蛋白,可与肝素结合,多糖链仅与其分泌功能有关,与生物活性无关。VEGF 121/165为可溶性分泌蛋白。VEGF 189/206几乎都结合在质膜或基底膜上的含有肝素的蛋白聚糖上。四种VEGF的生物活性无明显差异。VEGF是一类多功能生长因子,能特异性作用于血管内皮细胞,强烈促进其增殖,促进血管形成,并有升高血管通透性的作用。多种细胞有分泌VEGF的功能,并通过旁分泌方式作用于血管内皮细胞。对血管内皮细胞的促有丝分裂作用十分强烈,可明显促进血管生成,能引起血管通透性增加,且是最强烈的引起血管通透性增加的物质。1nmol/L即可起作用,为组胺的50 000倍。用于心血管疾病、肿瘤、创伤修复等。
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