EGFR抑制剂,EGFR inhibitor
1)EGFR inhibitorEGFR抑制剂
1.TheEGFR inhibitors were reviewed based on the various structures,and prospects and trends for development and application were discussed.笔者按照不同的结构分类,对EGFR抑制剂做了简要的介绍,并对其发展前景做了展望。
英文短句/例句
1.Progression in the mechanisms of EGFR inhibitors combined with radiotherapyEGFR抑制剂放射增敏机制的研究进展
2.Responses to Treatment with EGFR Inhibitor and Molecular Mechanisms of Intrinsic Resistance in Human Colon Cancer Cells;人结肠癌细胞对EGFR抑制剂敏感性的观察及其耐受机制的探讨
3.Enhancement of Radiation Cytotoxicity by Blocking EGFR and COX-2 Pathways in A549 Human Lung Cancer Cell Line联合COX-2及EGFR抑制剂对肺癌放射增敏的实验研究
4.EGFR-inhibitors Based Therapy Versus Non-EGFR-inhibitors Therapy in Metastatic Colorectal Cancer: A Meta-analysis of 10 Randomized Controlled Trials靶向药物-EGFR抑制剂治疗转移性结直肠癌的meta分析
5.Radiosensitivity Enhancement by Combined Treatment of COX-2 Inhibitor and EGFR Inhibitor on A549 Human Lung AdenocarcinomaCOX-2抑制剂与EGFR抑制剂联合应用对人肺腺癌A549细胞的放疗增敏的研究
6.The Relationship between EGFR Gene Mutations and the Response of Tyrosine Kinase Inhibitors in Patients with Advanced Non-small-cell Lung Cancer;EGFR基因突变与酪氨酸激酶抑制剂治疗晚期非小细胞肺癌疗效之间的关系
7.Heparin Inhibit Expressions of MUCIN5AC and Activity of EGFR in Pulmonary Epithelial Cell Line(A549) Stimulated by PMA肝素抑制佛波酯诱导A549细胞表达MUC5AC和EGFR活性
8.Inhibition of lung tumor growth in nude mice by siRNA targeting on EGFR靶向EGFR的siRNA有效抑制小鼠肺癌移植瘤的生长
9.Inhibitory effects of siRNA on expression of epidermal growth factor receptor in squamous cell carcinoma cell line A431RNAi抑制皮肤鳞癌A431细胞EGFR表达的实验研究
10.Inhibitory effects of targeting RNA of EGFR gene on the proliferation of human ovarian cancer cellsEGFR基因靶向RNA干扰抑制卵巢癌细胞增殖的研究
11.Effects of EGFR Downregulation via RNAi on Downstream Signal Transduction Pathways and Multi-drug Resistance Genes in Human Lung Adenocarcinoma Cell;RNAi抑制肺腺癌细胞EGFR表达对信号传导通路及耐药基因影响的研究
12.Effect of Ginsenoside Rg3 on the Epidermal Growth Factor Receptor Signaling Pathways in Human Breast Cancer Cell Line MCF-7;人参皂甙Rg3对MCF-7细胞EGFR信号传导通路的抑制作用
13.RNA interference targeting EGFR on proliferation of human ovarian carcinoma cell line SKOV_3靶向EGFR基因RNA干扰对人卵巢癌SKOV_3细胞增殖的抑制作用
14.Inhibitory effect of gefitinib combined with DNA vaccine targeting EGFR against mouse lung cancer Lewis cells吉非替尼联合靶向EGFR DNA疫苗对小鼠Lewis肺癌细胞体内外的抑制作用
15.Correlation between inhibition effect of gefitinib and epidermal growth factor receptorin nasopharyngeal carcinoma cells吉非替尼对鼻咽癌细胞抑制作用及其对EGFR表达影响的探讨
16.TGF-β Suppresses EGFR/MAPK Signaling and Proliferation in Asthmatic Epithelial CellsTGF-β抑制哮喘上皮细胞中EGFR/MAPK信号通路和细胞增殖
17.Study of EGFR gene repressed by RNAi on enhancing chemosensitivity of ovarian cancer cells to paclitaxelRNAi抑制EGFR基因增强卵巢癌细胞对泰素敏感性的研究
18.Inhibition effect of silencing EGFR gene by RNAi on tumorigenesis of xenograft tumor of ovarian cancerRNAi沉默EGFR基因在卵巢癌裸鼠移植瘤的成瘤抑制作用
相关短句/例句
EGFR inhibitorsEGFR抑制剂
1.The structures and functions of EGFR as well as current status ofEGFR inhibitors are reviewed.此文综述了EGFR的结构、功能以及EGFR抑制剂在胰腺癌治疗中的作用。
3)EGFR targeted inhibitorsEGFR靶向抑制剂
4)epidermal growth factor receptor tyrosine kinase inhibitorEGFR酪氨酸激酶抑制剂
1.Erlotinib,anepidermal growth factor receptor tyrosine kinase inhibitor;小分子EGFR酪氨酸激酶抑制剂盐酸埃罗替尼
5)inhibition of EGFR tyrosine kinases phosphorylationEGFR酪氨酸激酶抑制作用
6)checkpoint kinase 2(Chk2)inhibitorChk2抑制剂
延伸阅读
竞争性抑制剂分子式：CAS号：性质：产生竞争性抑制作用的抑制物。它与被抑制的酶的底物通常有结构上的相似性，能与底物竞相争夺酶分子上的结合位点，从而产生酶活性的可逆的抑制作用。如果抑制剂浓度恒定，则在低底物浓度([s])时抑制作用最为明显，增大[s]，抑制作用随之降低，直到[s]增大至很浓时，抑制作用近于消失，达到未加抑制剂时的最大反应速度(Vmax)水平，其动力学特征是：表观反应常数(Km)增大、Vmax不变。典型的例子如丙二酸和草酰乙酸对琥珀酸脱氢酶的抑制；磺胺药与对氨基苯甲酸(合成二氢叶酸的原料)抑制细菌二氢叶酸合成酶等。
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