乏氧诱导因子,HIF
1)HIF乏氧诱导因子
1.Experimental Studies on Regulation of hTERT in Malignant Tumor Cells byHIF α;乏氧诱导因子α调控恶性肿瘤细胞端粒酶表达的实验研究
英文短句/例句
1.Expression and Significance of Hypoxia of Inducible Factor-1α in Osteosarcoma;乏氧诱导因子1α在骨肉瘤中的表达及其意义
2.Study on Reversing Hypoxia-Induced Chemo-and Radio-resistances by Targeting on Hypoxia Inducible Factor-1α in Lung Cancer Cells;乏氧诱导因子-1α基因沉默逆转肺癌细胞放化疗耐受的研究
3.Anti-tumor effect of silencing Hif-1α and Survivin genes combined with X-ray irradiation on hypoxic tumor cells in vitro沉默乏氧诱导因子-1α和生存素基因联合X射线照射对乏氧细胞的体外抑瘤效应
4.Relationship between HIF-1 Alpha and Angiogenesis, Chemotherapy Response and the Mechanism in Esophageal Squamous Cell Carcinoma;乏氧诱导因子-1α与食管鳞癌血管生成和化疗疗效的关系及其机制
5.Experimental Studies on Regulation of hTERT in Malignant Tumor Cells by HIF α;乏氧诱导因子α调控恶性肿瘤细胞端粒酶表达的实验研究
6.Experimental Study of the Correlation between Hypoxia Inducible Factor-1a and Microvessel Density;乏氧诱导因子-1α与微血管密度表达水平相关性的实验研究
7.Expression of Hypoxia Inducible Factor-1α in Nasopharyngeal Carcinoma and Its Clinical Value乏氧诱导因子-1α在鼻咽癌中的表达及其临床意义
8.Construction of RNAi adenoviral shuttle vector targeting both HIF-1α and survivin synchronously靶向乏氧诱导因子-1α和生存素基因的RNA干扰腺病毒穿梭载体的构建
9.Influences of the p53 Status on Hypoxia-induced Gene Expression & Adenovirus-mediated Gene Therapy Targeting Tumor Hypoxia;p53对乏氧诱导基因表达的影响及腺病毒载体介导的肿瘤乏氧靶向性基因治疗
10.Resarch Progress in Hypoxia-inducible Factor Family and Lung Cancer低氧诱导因子家族与肺癌的研究进展
11.Cardioprotection role of hypoxia-inducible factor-1缺氧诱导因子-1在心肌保护中的作用
12.Relationship of hypoxia-inducible factor-1 and ischemic retinopathy低氧诱导因子-1与缺血性视网膜病变
13.Double effects of hypoxic-inducible factor in cerebral ischemia低氧诱导因子在脑缺血中的双重作用
14.The Expression of Hypoxia-inducible Factor-1alpha and Inducible Nitric Oxide Synthase in Inflammatory Bowel Disease;低氧诱导因子-1α、诱导型一氧化氮合酶在炎症性肠病中的表达
15.The Effects of Hypoixa-Inducible Factor-1a on Gastric Cancer During Hypoixa;缺氧诱导因子-1α对缺氧胃癌细胞的影响
16.The Study of Hypoxia Training and Hypoxia Inducible Factor-1;低氧训练与低氧诱导因子-1的研究进展
17.HIF-1 and the Regulatory Mechanism of Hypoxia Training;低氧诱导因子-1与低氧训练的调控机制
18.Gene Cloning of Hypoxia-inducible Factor-1α and Expression Research of HIF-1α-pcDNA3.1;缺氧诱导因子1α基因克隆及HIF-1α-pcDNA3.1表达研究
相关短句/例句
hypoxia inducible factor-1α乏氧诱导因子-1α
1.Objective To investigate the expression ofhypoxia inducible factor-1α(HIF-1α)and microvessels density(MVD),and further to evaluate the correlation between them.目的观察乏氧诱导因子-1α(HIF-1α)和微血管密度(MVD)在S180肉瘤中的表达水平,并探讨两者间的相关性。
2.Methods:A549 cell line(human lung adenocarcinoma) was cultured under hypoxic atmosphere(2% O_2) for 24 h,the expression ofhypoxia inducible factor-1α、P-gp and P53 protein was detected by immu.方法:乏氧条件下(2%O2)人肺腺癌细胞株A549体外培养24 h,免疫组化法检测乏氧诱导因子-1α(H IF-1α)、P-糖蛋白(P-gp)和P53蛋白的表达;MTT法检测乏氧条件下A549细胞在多柔比星作用下的存活率;应用流式细胞仪检测细胞凋亡。
3.Objective To investigate the correlation between the expression of DNA-dependent protein kinase (DNA-PK) andhypoxia inducible factor-1α (HIF-1α) induced by irradiation in hypoxic HeLa cell and the modulatory mechanism.目的初步探讨辐射效应诱导下乏氧人宫颈癌细胞系HeLa细胞乏氧诱导因子-1α(HIF-1α)和DNA依赖蛋白激酶(DNA-PK)表达相关性及其调控机制。
3)HIF-1α乏氧诱导因子-1α
1.Effects of silencingHIF-1α gene by RNA interference on Taxol-induced apoptosis of human esophageal squamous cell line EC9706;RNA干扰沉默乏氧诱导因子-1α对紫杉醇诱导食管鳞癌EC9706细胞凋亡的影响
2.Construction of RNAi adenoviral shuttle vector targeting bothHIF-1α and survivin synchronously靶向乏氧诱导因子-1α和生存素基因的RNA干扰腺病毒穿梭载体的构建
3.In order to investigate the anti-tumor effect of RNA interference silencingHIF-1α and Survivin genes combined with X-ray irradiation on hypoxic SMMC-7721 cells in vitro, we detected mRNA and protein expression ofHIF-1α and Survivin genes in hypoxic SMMC-7721 cells after transfection with pGenesil-Survivin-HIF carried by liposome by RT-PCR and Western blot respectively.为探讨RNA干扰(RNAinterference,RNAi)沉默乏氧诱导因子-1α(Hypoxia induced factor 1α,HIF-1α)和生存素(Survivin)基因联合X射线照射对乏氧人肝癌细胞SMMC-7721的体外抑瘤效应,利用双靶向HIF-1α和Survivin基因载体,采用阳离子脂质体介导法转染SMMC-7721细胞,经乏氧培养36h后,分别以RT-PCR和Western blot法检测HIF-1α和Survivin基因的mRNA及其蛋白表达,分别以四甲基偶氮唑盐(MTT)法和流式细胞术检测细胞存活分数及细胞凋亡。
4)hypoxia inducible factor-1乏氧诱导因子-1
1.Hypoxia could facilitate malignant cells metastasis,in which thehypoxia inducible factor-1 plays an important role.乏氧是实体瘤中普遍存在的现象,并且能引起肿瘤细胞一系列生物学行为的改变,如促进肿瘤转移,在此过程中乏氧诱导因子-1(hypoxia induc ib le factor-1,H IF-1)起着核心的作用。
5)Hypoxia inducible factor 1α乏氧诱导因子-1α
6)HIF-1α乏氧诱导因子1α
1.Objective To evaluate the feasibility ofHIF-1α(hypoxia induce factor-1α)expression and SPECT image with ~(99)Tc~m-EC-MNZ (~(99)Tc~m-EC-metronidazaole) in detecting tumor hypoxia,and to observe the correlation between these two methods.目的探讨肿瘤乏氧诱导因子1α(HIF1α)表达及乏氧显像剂99TcmEC甲硝唑(metronidazole,MNZ)SPECT显像对检测肿瘤乏氧(缺氧)程度的可行性,以及两种检测方法的相关性。
延伸阅读
正常人白细胞转移因子 , 白细胞转移因子,转移因子药物名称：转移因子英文名：Transfer Factor别名： 正常人白细胞转移因子 , 白细胞转移因子,转移因子外文名：Transfer Factor ,TF适应症： 为细胞免疫反应增强剂，能将细胞免疫活性转移给受体，以提高受体的免疫功能。临床上用于治疗某些抗生素难以控制的病毒性或酶菌性细胞内感染（如带状皰疹、流行性乙型脑炎、白色念珠菌感染等）。对恶性肿瘤可作为辅助治疗剂，对自体免疫性疾病也有一定治疗作用。 用量用法： 一般采用皮下注射，注于上臂内侧或大腿内侧腹股沟下端，１次注射１支，每周１～２次，１个月后改为每２周１次。对带状疱疹，一般只需注射１次。 规格： 注射液：每支２ｍｌ，相当于１×１０００００００００白细胞提取物（上海产）,北京产则相当于５～１０×1000000000. 注：严禁静脉给药.类别：免疫调节剂
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